Damage Control: Natural Selection Against Disease-Causing Mutations


The survival of the human species in the face of a high number of incoming genetic mutations has remained an important problem in evolutionary biology. A newborn human is estimated to receive about 70 new mutations that the parents did not have. While these provide a source of novelty for the species, a large fraction of them can also be damaging, or likely to interfere with the biological function that a gene has for the organism. So how do we not mutate into oblivion?