Technique offers detailed view of how RNA levels change
RNA plays a critical role in directing the creation of proteins, but there is more to the life of an RNA molecule than simply carrying DNA’s message. One can imagine that an RNA molecule is born, matures, and, eventually, meets its demise. Researchers at the Broad Institute of Harvard and MIT have developed an approach that offers many windows into the life cycle of these essential molecules and will enable other scientists to investigate what happens when something in a cell goes wrong. They describe their approach, which offers high resolution and a comprehensive scope, in a Nature Biotechnology article published online on April 24.